Karolinska Institutet, Dept of Medicine/Center for Infectious Medicine (CIM)

Description of research group and project
We are looking for a highly motivated post-doc with an interest in NK cell biology and translational medicine. The project concerns the development of new cell therapies based on insights into the functional heterogeneity of human NK cells. The studies involve basic molecular immunology with a strong translational component. The Malmberg Lab is located in Oslo/Norway and Stockholm/Sweden and currently consists of 17 people. Through partnerships with leading NK cell groups in Europe and the biotech industry we design and run clinical trials for patients with cancer.

Duties
The successful candidate will participate in the pre-clinical work aiming at launching the first in human cell therapy trial with adaptive NK cells. The projects involves basic aspects of human NK-cell development, differentiation and functional regulation. The postdoctoral fellow will be required to execute a variety of single-cell assays, including high-dimensional immune profiling by mass cytometry, flow cytometry, single-cell indexed FACS-sorting and RNA Seq. The postdoctoral fellow is expected to plan, execute, and analyze experiments in an independent manner and contribute scientifically to the group. In this particular position, the candidate will operate at the interface with our industrial partner and also contribute to the GMP scale up of the adaptive NK cell expansion protocol for clinical implementation. 

Entry requirements
The candidate must hold a PhD equivalent to a Swedish doctoral degree in the fields of immunology, cell biology, virology with publications in internationally renowned peer-reviewed journals. The candidate should be self-motivated, have good communications skills and ability to interact effectively and work productively in a team. Fluency in English is a requirement. Candidates should have a strong, documented background in single cell-based assessment of immunological responses. The ideal candidate has extensive experience in translational research, flow cytometry and functional immunological assays. In connection with the appointment of the post-doctoral position, we will accord special weight to academic skills, particularly demonstrated excellence in research, a strong dedication, and excellent communication skills. Work within the areas for the announcement is strongly considered as an additional qualification.

Application process
An application must contain the following documents in English:

  1. A personal letter explaining the interest in the position
  2. A complete curriculum vitae, including date of the thesis defence, title of the thesis, list of publications, previous academic positions, academic title, current position, academic distinctions, and committee work
  3. Contact details for two referees
  4. A summary of current work (no more than one page)
  5. Verifications for crediting of illness, military service, work for labour unions or student organisations, parental leave or similar circumstances

The application is to be submitted through the Varbi recruitment system.

The Center for Infectious Medicine, the Department of Medicine Huddinge, Karolinska Institutet
The Department of Medicine at Huddinge comprises of seven units, three research centers, and a total of around 70 independent research groups. Our ambition is to be a leading department within medical research and education. At the Center for Infectious Medicine (CIM) (http://www.ki.se/cim) research focuses on studies of the human immune system. The vision is to be a world leading translational research center within immunology.

Type of employment Visstidsanställning längre än 6 månader
Contract type Full time
Number of positions 1
Working hours 100 %
City Huddinge
County Stockholms län
Country Sweden
Reference number 2-3251/2018
Contact
  • Karl-Johan Malmberg, professor, kalle.malmberg@ki.se
Union representative
  • Mats Rudling, SACO, mats.rudling@ki.se
  • Yvonne Edlund OFR/ST , yvonne.edlund@ki.se
Published 07.Jun.2018
Last application date 29.Jun.2018 11:59 PM CET

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