Karolinska Institutet, Dept of Medicine/Center for Infectious Medicine (CIM)

The Department of Medicine at Huddinge comprises seven units, three research centers and, around 70 independent research groups. The Center for Infectious Medicine (CIM) is a research unit within the Department of Medicine Huddinge with a focus on translational studies of the human immune system and infection-immunity in humans. CIM has since its inauguration in 2002 rapidly grown and gained national and international recognition. The vision is to become one of the leading translational research centers within immunity and infectious diseases in Europe.

Research group and project
The research group where the announced position will be placed is headed by Tim Willinger and studies immune responses in mucosal tissues. To make our studies relevant to humans, we have developed innovative models that allow us to study the cells and function of the human immune system in vivo (Nature Biotechnology 32:364, 2014). The research assistant will participate in a project exploring the link between human innate lymphoid cell (ILC) migration, ILC function, and organ homeostasis in the lung in steady-state and inflammation.

The research assistant position includes the following tasks: Purification of human hematopoietic stem cells from cord blood, generation of mice with human immune system, analysis of human hematopoietic engraftment in blood, isolation of immune cells from the lung, flow cytometry of immune cells, analysis of flow cytometry data. In addition, the successful candidate will perform mouse procedures, such as injections and blood sampling.

Experience and competence
We are looking for a person with experience in immunology (such as cell isolation from blood and tissues, functional immunological assays), multicolor flow cytometry (including data analysis), and performing animal experiments. Previous work with genetically-modified mice, especially humanized mice, is of high merit.

The position requires a FELASA B certificate to work with mice. A Master’s degree in immunology is a great advantage. Moreover, the candidate should be highly motivated, have good communication skills, and the ability to interact effectively and work productively in a team of international researchers. Fluency in English is a requirement. Emphasis will be placed on technical competence, past experience with immunological methods and mouse models, as well as personal suitability.

Application process
The application is to be submitted on the MyNetwork recruitment system.

Type of employment Visstidsanställning längre än 6 månader
Contract type Full time
City Huddinge
County Stockholms län
Country Sweden
Reference number 2-2577/2018
  • Tim Willinger, tim.willinger@ki.se
Union representative
  • Mats Rudling, SACO, mats.rudling@ki.se
  • Yvonne Edlund OFR/ST , yvonne.edlund@ki.se
Published 07.May.2018
Last application date 28.May.2018 11:59 PM CET

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