Karolinska Institutet, Institutionen för biovetenskaper och näringslära, Toftgård (RTO)

The Department of Biosciences and Nutrition performs research and education in several areas of medical science including bioorganic chemistry, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, cellular virology, and nutrition. It offers an excellent international research and working environment, including around 300 scientists, students, administrative and technical personnel. The Department resides in the new biomedical research building Neo, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.

Research group and projects
We are looking for 1-3 postdoctoral researchers. The work will be performed in the laboratory of Rune Toftgård. We study the basic genetic and molecular mechanisms of Hedgehog signalling, the importance of this signalling pathway in cancer development, the  biology of tissue stem cells and interplay between tumour cells and the microenvironment. Successful applicants will perform studies on one of the following topics; mechanisms of and pharmacological modulation of Hedgehog signalling, the role of LGR6 expressing progenitor cells in breast carcinogenesis or understanding of paracrine Hedgehog signalling in colorectal cancer and liver metastasis.

The postdocs will be financed by scholarship and the period is for two years.

Qualifications and expectations
We are seeking goal-oriented candidates who thrives in an interdisciplinary and international environment. We expect candidates to have demonstrated experience in cell- and molecular biology and biochemistry. Experience of working with mice is advantageous. Ideal candidates are able to interact closely with the supervisor but at the same time are capable of independently progressing the project. Strong communication skills and English proficiency, both written and spoken, are required. You will present your data at lab meetings and at national and international conferences. The applicant is expected to apply for competitive national and international postdoctoral fellowships and will receive support in these endeavours.

Entry requirements
Scholarships for carrying out postdoctoral research may be granted to persons living in other countries who come to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education at KI. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships from KI. Qualified to be admitted as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish PhD or higher.

Type of scholarship
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. This educational scholarship is tax-exempt.

The amount is set for twelve months at a time and is paid out on a monthly basis. In exceptional cases, shorter periods may be acceptable.

Application process
An application must contain the following documents in English:

  1. A cover letter
  2. Curriculum vitae and qualifications, including date of thesis defence, title of thesis and current position
  3. A complete list of publications
  4. A summary of current work (no more than one page)
  5. Name, affiliation, phone number and email address of three references

The application is to be submitted on the Varbi recruitment system.

Reference number 2-1637/2018
  • Rune Toftgård, Senior Professor, +46+8-524 810 53
  • Thomas Tinglöv, Head of Administration, +46-8-524 835 49
Union representative
  • Henry Wölling, SEKO, +46-8-524 840 80
  • Birgitta Lindqvist, OFR, +46-8-524 810 28
Published 22.Mar.2018
Last application date 20.Apr.2018 11:59 PM CET

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