Karolinska Institutet, Institutionen för laboratoriemedicin

The Department of Laboratory Medicine consists of 6 divisions and is active in many areas of Laboratory Medicine. The department is involved in advanced basic scientific, clinical and epidemiological research. The department is one of the largest departments of education at Karolinska Institutet.

A Postdoctoral position (scholarship) is available with Assistant Professor Ujjwal Neogi at Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Campus Flemingsberg. The Division has two research groups in clinical bacteriology and five research groups in clinical virology. The research in clinical virology is focused on chronic viral infections such as HIV, hepatitis B, C and D, as well as Crim-Congo, Ebola and Zika virus.

Research Environment
The successful applicant will join an interactive, multidisciplinary team, (see http://ki.se/en/labmed/team-multi-omics-research) of seven researchers with background on molecular biology, virology, bioengineering, immunology and bioinformatics. The group uses an integrative and collaborative approach, and works closely with experimental, translational and clinical data driven research at LabMed, Science for Life Laboratory (SciLifeLab), Karolinska University Hospital and other local and international research groups. The research project is continuation of our recent finding which uses multi-omics (transcriptomics, proteomics and metabolomics) technology to understand the disease control mechanism in a group of HIV-1 positive individuals, who control viral replication and restrained progression to immunodeficiency, without any antiretroviral therapy (called Elite controllers) (Zhang et al 2017, EBioMedicine. PMID: 29269040, Sci Rep PMID:28386076). In this study, we would like to focus on two biological pathways, cell surface receptor signalling pathway and immune checkpoints and its cross-talk to identify the molecular mechanisms by which HIV-1 infection is controlled in EC. The study is funded by Swedish Research Council –Establishment grant to PI.

The successful applicant will apply standard molecular and cell biology techniques, e.g., molecular cloning, western blotting, confocal microscopy, immunoprecipitation, mammalian tissue culture, gene knockdown experiments and FACS are essential and participate in the general duties of the team. The candidate will take a strong lead in the project design and management as well as data generation, analyses and interpretation, and collaborate with other team members. A strong knowledge of immunology is required; molecular and cell biology preferred. The candidate should have strong publication track record as a first author in reputed peer-reviewed journals. An ideal candidate should be comfortable working both independently and in close collaboration with the PI on various projects related to this goal. The ability to work in a highly interdisciplinary and international environment, and to engage in continuous professional development is a must. The candidate is expected and encouraged to compete for early career young investigator funding.

Entry requirements
Scholarships for carrying out postdoctoral research may be granted to persons living in other countries who come to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education at KI. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships from KI. Qualified to be admitted as a postdoctor is one who has obtained a doctorate in Life Science, Medicine, Immunology or Molecular biology. Candidates must have successfully defended their thesis to be eligible for consideration.

Type of scholarship
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. This educational scholarship is tax-exempt.

The amount is set for twelve months at a time and is paid out on a monthly basis. In exceptional cases, shorter periods may be acceptable.

Application process
An application must contain the following documents in English:

  1. Curriculum vitae and qualifications, presented in accordance with Karolinska Institutet’s qualifications portfolio (http://ki.se/meritportfolj )
  2. A complete list of publications
  3. A summary of current work (no more than one page)
  4. Verifications for crediting of illness, military service, work for labour unions or studentorganisations, parental leave or similar circumstances

The application is to be submitted on the Varbi recruitment system.

Reference number 2-170/2018
  • Ujjwal Neogi , ujjwal.neogi@ki.se
Union representative
  • Emilie Hultin, SACO, 08-585 811 68, emilie.hultin@ki.se
  • Carina Eklund, OFR, 08-585 826 65, carina.eklund@ki.se
  • Karin Olsson, SEKO, karin.olsson@ki.se
Published 10.Jan.2018
Last application date 15.Apr.2018 11:59 PM CET

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