Karolinska Institutet, Institutionen för mikrobiologi, tumör- och cellbiologi, Lane

Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching in immunology, infection biology, cell biology and cancer. MTC has about 430 active employees, including 81 PhD students, 77 postdoctoral researchers and 32 professors. Key words are multidisciplinary, bridging, translational, national and international collaborations. 

The research group of Sir David Lane, FRS, is located at Karolinska Institutet in Solna and the SciLifeLab. The group consists currently of a PhD student, a lab manager, three postdocs, one assistant professor, two senior scientists, and a professor.

Our group works with all aspects of molecular biology to develop cancer treatment strategies. We focus particularly on the chemistry and biology of tumour suppressor proteins in the p53 pathway and how their central role in damage control and cell cycle regulation can be exploited therapeutically. Our lab includes state-of-the-art mass spectrometry, microscopy, and cell sorting facilities and closely collaborates with Sonia Laín’s chemical biology group at the Department of Microbiology, Tumor and Cell biology, KI, providing a unique environment for the study of cancer from the molecular to the organismal level.

The applicant will be focused on performing mass spectrometry (MS)-based proteomics studies consisting of sample preparation, liquid chromatography, data acquisition, and data handling. The applicant will work with the other members of the group by contributing proteome analysis, including phosphoproteomics, to various ongoing projects in the lab. Additionally, she/he may also develop own projects within the scope of the group's research. The position therefore requires a strong, well-documented track record of hands-on experience with all aspects of mass spectrometry-based proteomics. This includes the preparation of MS samples from cell culture and tissue material, handling and basic maintenance of LC-MS instrumentation (NanoMate, Orbitrap), and data processing and analysis using proteome databases.

Entry requirements
The successful candidate has a Master’s Degree in Clinical Chemistry, Biochemistry, or a related discipline. He or she is expected to have a strong drive to pursue experimental research, and an ambitious and innovative attitude. The applicant will work closely with other members of the group, and good collaborative skills are necessary. Emphasis will be put on personal skills in the evaluation process. Very good ability to speak and write in English is a requirement

Application process
The application is to be submitted on the MyNetwork recruitment system.

Type of employment Visstidsanställning 3-6 månader
Contract type Full time
Employment expires
Number of positions 1
Working hours 100 %
City Solna
County Stockholms län
Country Sweden
Reference number 2-5388/2017
  • Michael Landreh, Assistant professor, Michael.Landreh@ki.se
Union representative
  • Daisy Hjelmqvist SACO, daisy.hjelmqvist@ki.se
  • Henry Wölling, SEKO, henry.wolling@ki.se
  • Niklas Andersson, OFR, niklas.andersson@ki.se
Published 21.Nov.2017
Last application date 12.Dec.2017 11:59 PM CET

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