Karolinska Institutet, Institutionen för laboratoriemedicin

The Department of Laboratory Medicine consists of 6 divisions and is active in many areas of Laboratory Medicine. The department is involved in advanced basic scientific, clinical and epidemiological research. The department is one of the largest departments of education at Karolinska Institutet.

The Department of Laboratory of Medicine, located in Campus Flemingsberg, is one of the Karolinska Institutet’s largest departments with 8 research divisions including the Clinical Microbiology, where the project will be carried out. 350 people are employed at the department, half of which are PhD-students. The Centre provides the facilities needed for cell- and molecular biology research and the possibility to perform research in vivo.

The doctoral positions is an available doctoral education project to which a PhD student is to be recruited. After the selection process the process for admission to doctoral education will commence. An admission decision will not be taken until an individual study plan has been approved by the departmental admission board.

For more information regarding doctoral (PhD) education, see: http://www.ki.se/doctoral

Research group
The research group of Asst. Prof. Ujjwal Neogi is nested in a larger Anders Sonnerborg group. The aim of the research team is through translational research integrating multi-omics techniques and clinical data to understand the disease control mechanism in a group of HIV-1 positive individuals, who control viral replication and restrained progression to immunodeficiency, without any antiretroviral therapy for a longer duration of time (Elite controllers). 

The PhD students shall work on studies focussed around how a group of HIV-1 positive individual control HIV-1 infection naturally using transcriptomics, proteomics and metabolomics. The PhD positions are available for a bioinfomatician and laboratory work pertaining to molecular and cell biology/immunology. The study is funded by Swedish Research Council Establishment grant to the Dr. Neogi.

The doctoral education project and the duties of the student
There are two positions, one for bioinformatics component of the study where focus will be on developing methods and pipeline to integrate multi-omics data and another for cellular and molecular immunology related study, to perform mechanistic studies.

For the Bioinformatician, the candidate should have Master in Bioinformatics with strong programming skills (proficiency R, Perl and Unix). Prior experience with data generated by methods for Exome sequencing (genomics), RNAseq (transcriptomics) and amplicon sequencing to assemble the pathogen genome is desired. If the applicant has previous background in the industry that is a plus. A publication record in the field of NGS data analysis is a strong plus. A background in statistics and expertise in statistical methods for interpreting NGS data is desired. Prospective candidates should be high achievers and be able to work independently with experiments after initial instructions.

For the mechanistic study, we are looking for a highly motivated person with an interest in cellular and molecular immunology. The studies will include work on cell lines and primary cells. The candidate should have knowledge in high throughput Transcriptomics and proteomics study. A publication record in the field will be added advantage. Person should be willing to work with virus culture experiments at biosafety level 3.

Entry requirements for doctoral education at KI
To be eligible for doctoral education following requirements has to be met:

General entry requirements
A person meets the general entry requirements for doctoral/third-cycle/PhD education (according to Higher Education Ordinance Chapt 7, section 39) if he/she:

  1. has been awarded advanced/second-cycle/master qualification (i.e. master degree) or
  2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle/master level, or
  3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad.

Specific entry requirements
Proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school: Proficiency in the English language can be documented by an internationally recognized test such as TOEFL or IELTS, see web-link below for more information. Applicants who meet the general entry requirements (1 or 2 above) from a university in one of the Nordic countries fulfill the requirements in English.

For more information regarding general and specific entry requirements: http://ki.se/en/education/entry-requirements-eligibility-for-doctoral-education 

Assessment criteria
A selection will be made among qualified applicants on the basis of the ability to benefit from doctoral education. Karolinska Institutet uses the following bases of assessment:
- Documented subject knowledge of relevance to the area of research
- Analytical skill
- Other documented knowledge or experience that may be relevant to doctoral studies in the subject

The qualifications of the applicants will be evaluated on an overall basis.

Terms and conditions
All doctoral students at KI receive financial support during their doctoral education and employment on a doctoral studentship is the most common sort of support. During the time between recruitment and admission a short-term employment can be offered for up to 6 months.

Application process
An application must contain the following documents in Swedish or English:

  • A personal letter and curriculum vitae (Stating the which position you are applying) and curriculum vitae
  • A copy of degree certificates and associated certificates
  • A copy of degree projects and any previous publications
  • Letter of recommendation or the name of the referee.

The application is to be submitted through the MyNetwork recruitment system.

Type of employment Doktorandplats
Contract type Full time
Reference number 2-5537/2017
  • Ujjwal Neogi, +46 (0) 8524 83680
Union representative
  • Carina Eklund, OFR, 08-585 826 65, carina.eklund@ki.se
  • Emilie Hultin, SACO, 08-585 811 68, emilie.hultin@ki.se
  • Karin Olsson, SEKO, karin.olsson@ki.se
Published 27.Nov.2017
Last application date 17.Dec.2017 11:59 PM CET

Tillbaka till lediga jobb