At the Department of Oncology-Pathology basic, translational and clinical research and educational activities related to cancer is carried out. Approximately 300 people from over 40 nations are currently working at the department. 37 research groups with various cancer research profiles are involved and we have around 120 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.

Research group Olli Kallioniemi
This position resides in the research group of Olli Kallioniemi, Director of Science for Life Laboratory, Professor of Molecular Precision Medicine, affiliated with both the Dept. Oncology and Pathology, Karolinska Institutet and the Science for Life Laboratory. The work will involve an exciting opportunity to practice precision cancer medicine research in a translational setting, with the aim to assign and optimize targeted treatments for individual cancer patients. Our disease focus is on acute myeloid leukemia (AML), ovarian and urological tumors (prostate, kidney and bladder). Our goal is to develop a systems biology framework to match targeted therapies and drug combinations using genomic, transcriptomic and proteomic profiling along with functional ex vivo drug testing on primary patient-derived cells from cancer patients. We work through team science in close collaboration not only with other research groups, but also with clinicians, as well as with different technology platforms at the SciLifeLab. For more information: https://www.scilifelab.se/researchers/olli-kallioniemi/.

Qualifications
The successful candidate is expected to have a doctoral degree in biochemistry, biology, genetics, biotechnology, medicine or other relevant field. The candidate should ideally have previous experience working as a post-doctoral researcher, be independent and motivated with a documented ability to carry out experimental research projects but also project management, including excellent communication skills in spoken and written English. Previous expertise in developing patient-derived models from solid tumors and/or hematological cancers is beneficial. Experience on high-throughput drug testing, assay development, high-throughput and high-content microscopy or -omics technologies and associated bioinformatics is highly valued. We value interest and experience in collaborative team science in a multidisciplinary environment.

Task Description
The tasks for this position involves the establishment of innovative drug testing assays in primary cell models, characterization of the models and integration of the datasets to predict the response of patients to drug therapy. The candidate is also expected to carry out project management tasks, such as carrying out expected milestones within the project, budgeting and reporting, as well as interacting not only with research but also clinical and pharma collaborators.

Desired qualification and experience
- PhD in biochemistry, biology, genetics, biotechnology, medicine or other relevant field
- Knowledge of cancer biology, precision cancer medicine and translational cancer research
- Experience in high-throughput drug testing and assay development
- Experience in working as part of large multidisciplinary, collaborative research projects (“team science”)
- Extensive experience in cell culture techniques, especially primary cell models

Application process, salary and contract
An application must contain the following documents in English: Curriculum vitae, qualifications and description of previous research and career plans, presented in accordance with Karolinska Institutet’s qualifications portfolio. For more information: http://ki.se/qualificationsportfolio. The application is to be submitted through the MyNetwork recruitment system. The salary is defined according to the KI salary system. The project is initially for two year contract with the possibility of extension with the preferred start date as soon as possible.

Type of employment Visstidsanställning längre än 6 månader
Contract type Full time
Number of positions 1
Working hours 100%
City Solna
County Stockholms län
Country Sweden
Reference number 2-4247/2017
Contact
  • Päivi Östling, Associate Professor, Paivi.ostling@ki.se, +46 (0)736 735 762
Union representative
  • Andreas Lundqvist, SACO, 46 8 517 768 84, andreas.lundqvist@ki.se;
  • Mimmi Shoshan, SACO, 46 8 517 754 60
  • Helen Eriksson, OFR, 46 8 517 762 79
Published 19.Sep.2017
Last application date 19.Oct.2017 11:59 PM CET

Tillbaka till lediga jobb