The Institute of Environmental Medicine (IMM) is a department at Karolinska Institutet and an interdisciplinary research institution within the broad field of environmental medicine. IMM conducts cutting edge research within the areas of environmental and occupational medicine, toxicology, physiology, epidemiology, and biostatistics with the aim to clarify how environmental and lifestyle factors affect our health and which role genes have. IMM also serves as a scientific advisor to public authorities within the area of environmental medicine and IMM scientists participate in national and international expert groups.

A doctoral position is an available doctoral education project to which a PhD student is to be recruited. After the selection process the process for admission to doctoral education will commence. An admission decision will not be taken until an individual study plan has been approved by the departmental admission board.

For more information regarding doctoral (PhD) education, see:

Research group
Our research team is interested in the molecular signaling, which regulates the decision between life and death at the cellular level and how its deregulation is implicated in human diseases. The research group is led by Bertrand Joseph, and located at the Karolinska Institutet Solna Campus. 

The doctoral education project and the duties of the student

Microglia are the resident immune cells of the central nervous system, they constantly screen and interact with the brain environment. In the context of diseases, microglial activation can contribute to rather contrasting effects in in degenerative/traumatic versus proliferative diseases. Microglial are extremely plastic, and undergo a variety of structural and functional changes based on their location and current role. We want to elucidate the contribution of autophagy to a possible transcriptional resetting of microglia, which would allow their reprogramming towards a selective phenotype exerting unique functions in the healthy or pathologic brain.

We are seeking a highly motivated student to work on a project focused on the role of autophagy on microglia cell plasticity. You should like team-work and international contacts, yet be prepared to assume responsibility to deliver on your own parts in the project and fulfil the requirements of the doctoral training programme.

Entry requirements for doctoral education at KI
To be eligible for doctoral education following requirements has to be met:

General entry requirements
A person meets the general entry requirements for doctoral/third-cycle/PhD education (according to Higher Education Ordinance Chapt 7, section 39) if he/she:

  1. has been awarded advanced/second-cycle/master qualification (i.e. master degree) or
  2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle/master level, or
  3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad.

Specific entry requirements
Proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school:
Proficiency in the English language can be documented by an internationally recognized test such as TOEFL or IELTS, see web-link below for more information.
Applicants who meet the general entry requirements (1 or 2 above) from a university in one of the Nordic countries fulfill the requirements in English.

For more information regarding general and specific entry requirements:

Skills and personal qualities

Undergraduate training in biomedicine or cell molecular biology is required for enrollment. Students who have performed laboratory work in an area related to the project, and can document previous animal work experience would be an advantage. Candidates should be highly motivated, creative, and have strong communication skills. The ability to express oneself in speech and writing in English is a requirement. In addition, the aptitude to interact effectively and work productively in a team will be considered important.

Assessment criteria
A selection will be made among qualified applicants on the basis of the ability to benefit from doctoral education. Karolinska Institutet uses the following bases of assessment:
- Documented subject knowledge of relevance to the area of research
- Analytical skill
- Other documented knowledge or experience that may be relevant to doctoral studies in the subject

The qualifications of the applicants will be evaluated on an overall basis.

Terms and conditions
All doctoral students at KI receive financial support during their doctoral education and employment on a doctoral studentship is the most common sort of support. During the time between recruitment and admission a short-term employment can be offered for up to 6 months.

Application process
An application must contain the following documents in Swedish or English:

  • A personal letter and curriculum vitae
  • A copy of degree certificates and associated certificates
  • A copy of degree projects and any previous publications

The application is to be submitted through the MyNetwork recruitment system.

Type of employment Doktorandplats
Contract type Full time
Reference number 2-2588/2017
  • bertrand Joseph, professor ,
Union representative
  • Malahat Mousavi, SACO-S, 08-524 875 24
  • Henry Wölling, SEKO, 08-524 840 80,
  • Niklas Andersson, OFR , 08-524 874 19
Published 15.Jun.2017
Last application date 06.Jul.2017 11:59 PM CET

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