Established in June 2013, the Karolinska Institutet/AstraZeneca Integrated Cardio Metabolic Centre (KIAZ ICMC) represents a unique and exciting opportunity for academic scientists to collaborate and work side-by-side with scientists from the pharmaceutical industry to discover and develop the next generation of medicines to treat cardiovascular and metabolic diseases. More information about AZ/KI ICMC can be found at http://ki.se/en/medh/integrated-cardio-metabolic-centre-icmc                      

Description of the research group

The central scientific interest of Myriam Aouadi’s lab is to understand the interaction between the immune system and metabolism at the molecular and cellular level, with the ultimate goal of applying the developmental principles, logic, pathways, technology, and model systems to unravel human metabolic disease. We use several different approaches to study immunometabolic diseases, including next generation sequencing, gene manipulation and in vivo systems. 

Responsibilities

We are seeking a candidate with an extensive background in experimental laboratory work. Applicants should be familiar with experimental methods used to study metabolic diseases and immunology.

You will work closely with researchers and assist in the introduction of the laboratory for new staff, guest researchers and graduate students as well as with the development and improvement of experimental methods. 

Entry requirements

  • Must hold a Master degree
  • Strong expertise working with mice and particularly mouse models of metabolic diseases
  • Documented experience with animal experimentation (Felasa certification)
  • Excellent in vitro laboratory skills
  • Strong expertise in flow cytometry
  • Strong expertise in library preparation for single cell and bulk RNAseq
  • Excellent experience working with small interfering RNA and their delivery in vivo
  • Histology, immunohistochemistry, in situ hybridization techniques
  • Experience in isolation of macrophages from liver and adipose tissue
  • Ability to maintain good relationship with the department and animal facility as well as with external collaborators

  • Support of all the projects in the lab
  • Excellent organizational skills
  • The applicant must speak and write fluent English and Swedish

Personal skills

Excellent interpersonal skills are required. Emphasis will be placed on qualities as responsibility, flexibility, teamwork and ability to solve problems. 

Application process

The application must contain the following documents in English: 

  • Cover letter
  • CV including contact details of at least 2 reference persons
  • Copy of degree certificates and grades

The application is to be submitted on the MyNetwork recruitment system.

At Karolinska Institutet a 6-month trial period is required for all permanent appointments.

Type of employment Tillsvidareanställning
Contract type Full time
City Stockholm
County Stockholms län
Country Sweden
Reference number 2-2446/2017
Contact
  • Myriam Aouadi, myriam.aouadi@ki.se
Union representative
  • Mats Rudling, SACO, mats.rudling@ki.se
  • Yvonne Edlund OFR/ST , yvonne.edlund@ki.se
Published 12.May.2017
Last application date 26.May.2017 11:59 PM CET

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