Karolinska Institutet, Department of Medical Biochemistry and Biophysics, MIR

A Scientific Project Coordinator position in a project to develop a new diagnostic assay for rheumatoid arthritis is now open. This position is sponsored by the Swedish Foundation for Strategic Research (SSF) for the network JointID “Biomarkers predicting joint inflammation”. It is placed at the Section for Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, at the Karolinska Institutet, Sweden.

Job description:
Section for Medical Inflammation Research is searching for a Scientific Project Coordinator to work in a project supported by the Swedish Foundation for Strategic Research (SSF) in Sweden and led by Prof. Rikard Holmdahl. The task is to coordinate, as part of the coordinating team, the scientific research work conducted within the JointID network, and to coordinate transfer and analysis of samples and clinical data of large human cohorts in collaboration with the participating clinicians. The tasks include scientific reporting and writing grant applications as well as developing the test to meet the regulatory requirements of commercialization. In addition to the coordinator tasks, the candidate is expected to conduct scientific research to develop multiplex assays for detection of antibodies to defined protein epitopes and to analyze these in depth in both experimental animal models and human samples.

The project:
The JointID project aims at developing a diagnostic test for rheumatoid arthritis and other joint inflammatory diseases. The test is based on unique antigenic epitopes derived from various joint proteins. The epitopes have been formulated as conformational peptides but needs to be further improved regarding their functional and diagnostic role. As these peptides and epitopes are similar in mice and humans, there are possibilities to make in depth functional analysis in the mouse as well as to test human sera for assay development.

The assay development will be based on a multiplex platform, and the peptides will be analyzed in detail regarding their physical properties e.g. utilizing solid-phase assays like ELISA to compare with the multiplex technology. The goal is to develop a sensitive and specific diagnostic test and to publish the results in leading international journals.

We are looking for an ambitious candidate with excellent planning, organizational and problem solving skills. The successful applicant must have the ability to work independently with a conscientious working attitude but also to be a good team player and to actively interact with colleagues.
To qualify, the applicant must hold a PhD in medicine or biological science and have several years of experience and excellence in practical laboratory work. Experience in conducting animal experiments and the license for animal experimentation are also required as well as experience in working with large human cohorts and handling human material. Proven ability to manage a research project including grant applications, budgeting, reporting, and managing collaborations across institutions is a requirement. Knowledge in communicating in spoken and written English and easiness with social communication are absolute requirements. To qualify, the applicant must have good communication skills in spoken and written Swedish. Knowledge in bioinformatics and statistical methods is needed.

Application process
The application is to be submitted on the MyNetwork recruitment system.

At Karolinska Institutet a 6-month trial period is required for all permanent appointments.

Type of employment Visstidsanställning längre än 6 månader
Contract type Full time
Working hours 100 %
City Solna
County Stockholms län
Country Sweden
Reference number 2-2025/2017
  • Rikard Holmdahl, profeeor, 08-524 846 07
Union representative
  • Biborka Bereczky Veress, SACO, 46 70-173 85 75
  • Anne Edgren, OFR/S, P, O, 08-616 16 29
  • Henry Wölling, SEKO, 08-524 840 80
Published 13.Apr.2017
Last application date 16.May.2017 11:59 PM CET

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