Karolinska Institutet is one of Europe's largest medical universities. It is also Sweden’s largest centre for medical training and research, accounting for 30 per cent of the medical training and 40 per cent of the medical academic research that is conducted nationwide. Karolinska Institutet´s mission is to improve the health of mankind through research, education and information.
The VirusTech core facility
Viruses have emerged as useful tools for efficient delivery of genes to mammalian cells. Thus, it is no wonder that viruses have led the field in gene therapy, as they have evolved to deliver their genes efficiently, in the form of either RNA or DNA into mammalian cells. In research, delivery of genetic information to cellular systems is the backbone of many experiments. The delivery of recombinant genes into neurons is a critically important strategy for understanding the molecular mechanisms underlying brain function, as well as for how these mechanisms go awry in brain disorders. A complementary and equally important strategy is delivery of genetic tools affecting gene expression to over-express, reduce or eliminate a specific RNA or protein.
The core facility specializes in the production and concentration of Lentiviral and Adeno Associated Viruses (AAVs), but it aims to develop and optimize the production of other types of viruses such as Canine Adenovirus, retroviruses, Rhabdo viruses and Herpes simplex viruses. Its primary purpose is to produce and distribute quality viral vectors to researchers within Karolinska Institutet and thereafter investigators world-wide. The core facility is now looking for a lab technician with interest and experience in BSL-2 level work with different types of virus vectors in general and AAVs in particular.
Your role as a lab technician
As you would be directly involved in the production of viruses and mainly working within the BSL-2 lab, your responsibilities would include (but are not limited to):
Qualifications and requirements
Since the facility will handle the production of viruses from different customers from Karolinksa Institutet as well as from other institutions, we are looking for a highly organized, self-motivated person with excellent time management skills who can work effectively in a dynamic and diverse laboratory setting. Experience in biosafety level 2 or higher work for the production and handling of infectious particles, especially Adeno Associated Viruses (AAVs), is meriting. You are structured and organized in your approach to work but flexible and receptive to developmental challenges. You also have good social and interpersonal skills, since you will be working in a multicultural environment, and routinely report progress to the Core facility manager and directors.
The application is to be submitted on the MyNetwork recruitment system.
|Type of employment||Visstidsanställning längre än 6 månader|
|Contract type||Full time|
|Last application date||31.Mar.2017 11:59 PM CET|