Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Chemistry II

A two-year post-doctoral position is available at the Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet, Stockholm. The project deals primarily with over-expression, purification, crystallization and structure determination of human membrane proteins involved in the generation of lipid mediators of inflammation.

The successful candidate will join a multi-disciplinary research team and the position represents an opportunity for a postdoctoral scientist to develop their expertise as well as broaden their experience. The major interests of the lab are in membrane protein structure and function. We combine structural techniques such as macromolecular crystallography with biophysical, biochemical and computational methods to investigate the structural basis of catalysis. The lab has all necessary equipment and access to facilities needed for the project, including a core facility for protein science. We have periodic access to beamlines at ESRF (France), Diamond (UK), BESSY and DESY (Germany).

Chemistry II is an inter-disciplinary division of medical research including researchers specializing in structural biology, biochemistry and biophysics, in vitro and in vivo models of disease and mass-spectrometry platforms for metabolomics.

The successful candidate will perform all aspects of macromolecular structure determination, including molecular cloning, protein expression and purification, protein crystallization, X-ray data collection at synchrotron light sources and subsequent processing. The candidate will also participate in biochemical and biophysical confirmation of function, analysis of data and writing of associated manuscripts for publication.

Entry requirements
Scholarships to pursue postdoctoral studies may be awarded to individuals who come from other countries with the intention of remaining in Sweden only while obtaining all or part of their education. Having received a salary or other remuneration from Karolinska Institutet during the past two years may be disqualifying.

The applicant must have graduated from their PhD not more than two years ago and be motivated to independently solve problems and a have a strong background in biochemistry or structural biology. Experience with protein expression, purification and biochemical characterization is required.  Prior experience in membrane protein biochemistry and computational skills such as a familiarity with the LINUX operating system will be added advantages.

Type of scholarship
Karolinska Institutet awards scholarships to pursue postdoctoral studies.  This educational scholarship is tax-exempt. The amount is set for twelve months at a time and is paid out on a monthly basis. 

Application process
An application must contain the following documents in English:

  1. Curriculum vitae and qualifications, presented in accordance with Karolinska Institutet’s qualifications portfolio (http://ki.se/meritportfolj )
  2. A complete list of publications
  3. A summary of current work (no more than one page)
  4. Verifications for crediting of illness, military service, work for labour unions or studentorganisations, parental leave or similar circumstances

The application is to be submitted on the MyNetwork recruitment system.

Type of employment Postdoktoralt stipendium
Contract type Full time
Reference number 2-1021/2017
  • Dr Joseph Brock, +46 (0)8-524 800 00
  • Prof Jesper Haeggström, +46 (0)8-524 800 00
Union representative
  • Anne Edgren, OFR/S, P, O, +46 (0)-8-616 16 29
  • Biborka Bereczky Veress, SACO, +46 (0)70-173 85 75
  • Henry Wölling, SEKO, +46 (0)8-524 840 80
Published 23.May.2017
Last application date 13.Jun.2017 11:59 PM CET

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